Re:

I know but I'm looking for anecdotal evidence. Success stories from real people who used topical keto for x months. I have yet to find one. Nevertheless I strongly believe in keto !

Background 5-Lipoxygenase activity is enhanced in peripheral blood mononuclear cells (PBMC) from end-stage renal disease (ESRD) patients on maintenance hemodialysis (HD), leading to lipoperoxidation and reactive oxygen species formation. These effects are prevented by vitamin E, which inhibits 5-lipoxygenase activity. The present study was designed to test the possibility that 5-lipoxygenase activation might cause mitochondrial damage and cytochrome c release, ultimately leading PBMC to apoptosis.

Methods Apoptosis, mitochondrial uncoupling, and cytochrome c release were investigated in PBMC from 16 healthy volunteers and 16 ESRD patients on maintenance HD with cuprammonium rayon (CL-S) membranes in a two-step crossover study: after a four-week treatment with vitamin E-coated cuprammonium rayon (CL-E) membranes, and again after a four-week treatment with oral vitamin E.

Results Compared to healthy controls, PBMC from ESRD patients showed a threefold increase in mitochondrial uncoupling and cytochrome c release (within 4 and 8 hours, respectively), followed by a threefold increase in apoptotic body formation (within 48 hours). Regardless of the administration route, vitamin E reduced mitochondrial uncoupling, cytochrome c release and apoptosis of mononuclear cells, as did the 5-lipoxygenase inhibitor eicosatetraynoic acid. Conversely, the cyclooxygenase inhibitor indomethacin was ineffective.

Conclusions Reported data suggest that the 5-lipoxygenase branch of the arachidonate cascade is only responsible for mitochondrial disruption and apoptosis of PBMC of ESRD patients, and that vitamin E may be helpful in the control of oxidative stress-related disease in these subjects, independent of the administration route.

http://www.nature.com/ki/journal/v63/n84s/full/4493764a.html

If anyone has any information I personally would greatly appreciate you relaying it to us all.

Then there's one other thing. Nizoral shampoo is too harsh to use everyday for most people but Regenpure probably isn't....haven't personally used it but I suspect it would be easier on the scalp. Perhaps using a shampoo that contains keto everyday would work much better.

I thought keto is soluable in alcohol?